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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619757
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acox1
Name: acyl-CoA oxidase 1
Acc ID: CHEBI:15525
Term: palmitoyl-CoA
Definition: A long-chain fatty acyl-CoA resulting from the formal condensation of the carboxy group of hexadecanoic acid with the thiol group of coenzyme A.
Chemical ID: MESH:D010171
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acox1increases metabolic processingISOAcox1 (Mus musculus)6480464CTDACOX1 protein results in increased metabolism of Palmitoyl Coenzyme APMID:10497882
Acox1multiple interactionsISOAcox1 (Mus musculus)6480464CTD[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide; benz(a)anthracene promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Dehydroepiandrosterone promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Tetrachlorodibenzodioxin promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]PMID:10497882
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