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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619754
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Smpd3
Name: sphingomyelin phosphodiesterase 3
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Smpd3affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of SMPD3 mRNAPMID:22298810
Smpd3decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of SMPD3 mRNAPMID:21215274 PMID:21964420
Smpd3affects expressionISOSmpd3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of SMPD3 mRNAPMID:21570461
Smpd3decreases expressionISOSmpd3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SMPD3 mRNAPMID:20005886
Smpd3increases expressionISOSMPD3 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of SMPD3 mRNAPMID:23152189
Smpd3increases expressionISOSmpd3 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of SMPD3 mRNAPMID:19933214
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