Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61972
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc15a2
Name: solute carrier family 15 member 2
Acc ID: CHEBI:8774
Term: ramipril
Definition: A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.
Chemical ID: MESH:D017257
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc15a2multiple interactionsEXP 6480464CTDRamipril inhibits the reaction [SLC15A2 protein results in increased uptake of glycylsarcosine]PMID:18713951
Go Back to source page   Continue to Ontology report