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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61956
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nt5e
Name: 5' nucleotidase, ecto
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nt5eincreases expressionEXP 6480464CTDOzone results in increased expression of NT5E proteinPMID:33146391
Nt5eincreases expressionISONT5E (Homo sapiens)6480464CTDOzone results in increased expression of NT5E mRNAPMID:31476115
Nt5emultiple interactionsISONt5e (Mus musculus)6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of NT5E mRNA; [Air Pollutants results in increased abundance of Ozone] which results in increased expression of NT5E mRNAPMID:34911549
Nt5emultiple interactionsISONT5E (Homo sapiens)6480464CTD[Aripiprazole co-treated with Ozone] results in increased expression of NT5E mRNAPMID:31476115
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