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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61877
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Psmb4
Name: proteasome 20S subunit beta 4
Acc ID: CHEBI:86989
Term: stattic
Definition: A member of the class of 1-benzothiophenes that is 1-benzothiophene-1,1-dioxide substituted at position 6 by a nitro group. Used as a radiosensitising agent for esophageal squamous cell carcinoma.
Chemical ID: MESH:C517409
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Psmb4decreases expressionISOPSMB4 (Homo sapiens)6480464CTDstattic results in decreased expression of PSMB4 mRNA; stattic results in decreased expression of PSMB4 proteinPMID:24627483
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