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GENE - TERM ANNOTATION REPORT

RGD ID: 61817
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Col1a1
Name: collagen type I alpha 1 chain
Acc ID: DOID:9004914
Term: Postmenopausal Osteoporosis
Definition: Metabolic disorder associated with fractures of the femoral neck, vertebrae, and distal forearm. It occurs commonly in women within 15-20 years after menopause, and is caused by factors associated with menopause including estrogen deficiency.
Definition Source(s): MESH:D015663
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col1a1 ISOCOL1A1 (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Postmenopausal osteoporosisPMID:10931857 PMID:12590186 PMID:15024692 PMID:15241796 PMID:15864348 PMID:15931785 PMID:16199547 PMID:16879195 PMID:17078022 PMID:17309652 PMID:18412368 PMID:18553566 PMID:18704262 PMID:19344236 PMID:19358256 PMID:2037280 PMID:21249479 PMID:21567126 PMID:21667357 PMID:22589248 PMID:22753364 PMID:22855962 PMID:24390061 PMID:25086671 PMID:2542316 PMID:25741868 PMID:25944380 PMID:25963598 PMID:26177859 PMID:26467025 PMID:27509835 PMID:27510842 PMID:27519266 PMID:28378289 PMID:28492532 PMID:28810924 PMID:31447884 PMID:32166892 PMID:33228694 PMID:33928192 PMID:33939306 PMID:7695699 PMID:7942841 PMID:8218237 PMID:8408653 PMID:8669434 PMID:8808594 PMID:9016532 PMID:9067755 PMID:9295084 PMID:9443882
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