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GENE - TERM ANNOTATION REPORT

RGD ID: 61808
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Faah
Name: fatty acid amide hydrolase
Acc ID: DOID:303
Term: substance-related disorder
Definition: A disease of mental health involving the abuse or dependence on a substance that is ingested in order to produce a high, alter one's senses, or otherwise affect functioning. (DO)
Definition Source(s): https://www.psychologytoday.com/us/conditions/substance-related-disorders "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Faah ISOFAAH (Homo sapiens)1300311RGDDNA:missense mutation:cds:p.P129T (human) 
Faah ISOFAAH (Homo sapiens)1625741RGD  
FaahsusceptibilityISOFAAH (Homo sapiens)7240710OMIM  
Faah ISOFAAH (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:12060782 PMID:19103437
Faah ISOFAAH (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Polysubstance abuse, susceptibility toPMID:12060782 PMID:15254019 PMID:16972078 PMID:23556448 PMID:25741868
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