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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3972
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Wnt3
Name: Wnt family member 3
Acc ID: CHEBI:232612
Term: Azoxymethane
Definition: A potent carcinogen and neurotoxic compound. It is particularly effective in inducing colon carcinomas. (PubChem)
Chemical ID: MESH:D001397
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Wnt3multiple interactionsISOWnt3 (Mus musculus)6480464CTD[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of WNT3 mRNA; celastrol inhibits the reaction [[Dextran Sulfate co-treated with Azoxymethane] results in increased expression of WNT3 mRNA]PMID:31715269
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