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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3931
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ucp1
Name: uncoupling protein 1
Acc ID: CHEBI:16856
Term: glutathione
Definition: A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine.
Chemical ID: MESH:D005978
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ucp1multiple interactionsEXP 6480464CTDGlutathione inhibits the reaction [alitretinoin results in increased expression of UCP1 mRNA]; Glutathione inhibits the reaction [rosiglitazone results in increased expression of UCP1 mRNA]PMID:12414803
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