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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:278547
Term: sodium azide
Definition: The sodium salt of hydrogen azide (hydrazoic acid).
Chemical ID: MESH:D019810
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfincreases expressionEXP 6480464CTDSodium Azide results in increased expression of TNF proteinPMID:36249784
Tnfmultiple interactionsEXP 6480464CTD[bergenin co-treated with 2,2-bis(4-glycidyloxyphenyl)propane] inhibits the reaction [Sodium Azide results in increased expression of TNF protein]; [Sodium Azide co-treated with bergenin] results in increased expression of TNF protein; [Sodium Azide co-treated with Donepezil] results in increased expression of TNF protein; Sodium Azide promotes the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]PMID:36249784 PMID:7539275
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