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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3865
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Timp3
Name: TIMP metallopeptidase inhibitor 3
Acc ID: CHEBI:31835
Term: methylparaben
Definition: A 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries.
Chemical ID: MESH:C015358
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Timp3decreases expressionISOTIMP3 (Homo sapiens)6480464CTDmethylparaben results in decreased expression of TIMP3 mRNAPMID:38568856
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