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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3749
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Spink1
Name: serine peptidase inhibitor, Kazal type 1
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Spink1affects expressionEXP 6480464CTDCarbon Tetrachloride affects the expression of SPINK1 mRNAPMID:16239168
Spink1increases expressionEXP 6480464CTDCarbon Tetrachloride results in increased expression of SPINK1 mRNAPMID:30723492 PMID:31150632
Spink1increases expressionISOSpink1 (Mus musculus)6480464CTDCarbon Tetrachloride results in increased expression of SPINK1 mRNAPMID:27339419 PMID:29987408 PMID:31919559
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