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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3735
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sox10
Name: SRY-box transcription factor 10
Acc ID: CHEBI:75393
Term: Y-27632
Definition: A monocarboxylic acid amide that is trans-[(1R)-1-aminoethyl]cyclohexanecarboxamide in which one of the nitrogens of the aminocarbony group is substituted by a pyridine nucleus. It has been shown to exhibit inhibitory activity against Rho-associated protein kinase (ROCK) enzyme.
Chemical ID: MESH:C108830
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sox10increases expressionEXP 6480464CTDY 27632 results in increased expression of SOX10 mRNAPMID:20578043
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