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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3731
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sod1
Name: superoxide dismutase 1
Acc ID: CHEBI:16643
Term: L-methionine
Definition: The L-enantiomer of methionine.
Chemical ID: MESH:D008715
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod1decreases expressionEXP 6480464CTDMethionine results in decreased expression of SOD1 mRNAPMID:27900820
Sod1multiple interactionsISOSod1 (Mus musculus)6480464CTD[Choline deficiency co-treated with Methionine deficiency] results in decreased expression of SOD1 mRNA; [Methionine deficiency co-treated with Choline deficiency] results in decreased expression of SOD1 mRNA; Bezafibrate inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in decreased expression of SOD1 mRNA]; pioglitazone inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in decreased expression of SOD1 mRNA]PMID:18513333 PMID:29097836
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