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GENE - TERM ANNOTATION REPORT

RGD ID: 3714
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc6a4
Name: solute carrier family 6 member 4
Acc ID: DOID:0050848
Term: obstructive sleep apnea
Definition: A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Obstructive_sleep_apnea "DO" "DO", http://www.mayoclinic.org/diseases-conditions/sleep-apnea/basics/definition/con-20020286 "DO" "DO", http://www.nlm.nih.gov/medlineplus/ency/article/000811.htm "DO" "DO", https://www.ncbi.nlm.nih.gov/books/NBK63555/#executivesummary.s1 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc6a4 ISOSLC6A4 (Homo sapiens)4889462RGDDNA:polymorphism, repeat:promoter, intron (human) 
Slc6a4no_associationISOSLC6A4 (Homo sapiens)4889463RGDDNA:polymorphism:promoter (human) 
Slc6a4no_associationISOSLC6A4 (Homo sapiens)4889466RGDDNA:polymorphism, repeat:promoter, intron (human) 
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