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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3704
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc2a1
Name: solute carrier family 2 member 1
Acc ID: CHEBI:9144
Term: silibinin
Definition: A flavonolignan isolated from milk thistle, Silybum marianum, that has been shown to exhibit antioxidant and antineoplastic activities.
Chemical ID: MESH:C440975
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc2a1decreases expressionISOSLC2A1 (Homo sapiens)6480464CTDSilybin results in decreased expression of SLC2A1 proteinPMID:34053323
Slc2a1multiple interactionsISOSLC2A1 (Homo sapiens)6480464CTD3-methyladenine promotes the reaction [Silybin results in decreased expression of SLC2A1 protein]; dorsomorphin promotes the reaction [Silybin results in decreased expression of SLC2A1 protein]PMID:34053323
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