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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3691
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc16a7
Name: solute carrier family 16 member 7
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc16a7decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLC16A7 mRNAPMID:21215274 PMID:32109520
Slc16a7affects expressionISOSLC16A7 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of SLC16A7 mRNAPMID:22298810
Slc16a7affects expressionISOSlc16a7 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of SLC16A7 mRNAPMID:20702594 PMID:28213091
Slc16a7increases expressionISOSLC16A7 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin results in increased expression of SLC16A7 mRNAPMID:19619570 PMID:20106945 PMID:21632981
Slc16a7increases expressionISOSlc16a7 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of SLC16A7 mRNAPMID:28922406
Slc16a7multiple interactionsISOSLC16A7 (Homo sapiens)6480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of SLC16A7 mRNAPMID:19619570
Slc16a7multiple interactionsISOSlc16a7 (Mus musculus)6480464CTDTetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SLC16A7 gene]PMID:28213091
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