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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3689
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc14a2
Name: solute carrier family 14 member 2
Acc ID: CHEBI:46195
Term: paracetamol
Definition: A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
Chemical ID: MESH:D000082
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc14a2affects expressionISOSlc14a2 (Mus musculus)6480464CTDAcetaminophen affects the expression of SLC14A2 mRNAPMID:17562736
Slc14a2increases expressionISOSlc14a2 (Mus musculus)6480464CTDAcetaminophen results in increased expression of SLC14A2 mRNAPMID:26176337
Slc14a2multiple interactionsISOSlc14a2 (Mus musculus)6480464CTD3-(4-chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one inhibits the reaction [SB 657510 inhibits the reaction [Acetaminophen results in increased expression of SLC14A2 mRNA]]; SB 657510 inhibits the reaction [Acetaminophen results in increased expression of SLC14A2 mRNA]PMID:26176337
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