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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3656
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Selp
Name: selectin P
Acc ID: CHEBI:15843
Term: arachidonic acid
Definition: A long-chain fatty acid that is a C20, polyunsaturated fatty acid having four (Z)-double bonds at positions 5, 8, 11 and 14.
Chemical ID: MESH:D016718
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Selpincreases expressionISOSELP (Homo sapiens)6480464CTDArachidonic Acid results in increased expression of SELP proteinPMID:18413191 PMID:23249183
Selpmultiple interactionsISOSELP (Homo sapiens)6480464CTDAspirin inhibits the reaction [Arachidonic Acid results in increased expression of SELP protein]; Glucose inhibits the reaction [Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of SELP protein]]; Quercetin inhibits the reaction [Arachidonic Acid results in increased expression of SELP protein]PMID:17543677 PMID:18413191 PMID:23249183
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