GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rxra | decreases degradation | ISO | RXRA (Homo sapiens) | 6480464 | CTD | Dimethylformamide results in decreased degradation of RXRA protein | PMID:31875996 | Rxra | increases phosphorylation | ISO | RXRA (Homo sapiens) | 6480464 | CTD | [Dimethylformamide results in increased phosphorylation of MAPK1 protein] which results in increased phosphorylation of RXRA protein; [Dimethylformamide results in increased phosphorylation of MAPK3 protein] which results in increased phosphorylation of RXRA protein | PMID:31875996 | Rxra | multiple interactions | ISO | RXRA (Homo sapiens) | 6480464 | CTD | Alitretinoin inhibits the reaction [Dimethylformamide results in decreased degradation of RXRA protein]; Dimethylformamide promotes the reaction [NFE2L2 protein binds to RXRA protein]; U 0126 inhibits the reaction [Dimethylformamide results in decreased degradation of RXRA protein] | PMID:31875996 | |
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