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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3426
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Psmb8
Name: proteasome 20S subunit beta 8
Acc ID: CHEBI:28094
Term: 2,2,2-trichloroethanol
Definition: A chloroethanol that has formula C2H3Cl3O.
Chemical ID: MESH:C005849
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Psmb8multiple interactionsISOPSMB8 (Homo sapiens)6480464CTD[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of PSMB8 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [[HLA-B protein alternative form co-treated with 2,2,2-trichloroethanol] results in increased expression of PSMB8 protein]PMID:36423715
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