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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3403
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prl
Name: prolactin
Acc ID: CHEBI:49584
Term: 4-ethylphenol
Definition: A member of the class of phenols carrying an ethyl substituent at position 4.
Chemical ID: MESH:C042291
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prlincreases secretionEXP 6480464CTD4-ethylphenol results in increased secretion of PRL proteinPMID:19479013
Prlincreases secretionISOPrl (Mus musculus)6480464CTD4-ethylphenol results in increased secretion of PRL proteinPMID:20950447
Prlmultiple interactionsISOPrl (Mus musculus)6480464CTD4-ethylphenol affects the reaction [Estriol results in increased secretion of PRL protein]; 4-ethylphenol inhibits the reaction [Estradiol results in increased secretion of PRL protein]; 4-ethylphenol inhibits the reaction [Estrone results in increased secretion of PRL protein]PMID:20950447
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