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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3305
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pf4
Name: platelet factor 4
Acc ID: CHEBI:9271
Term: stevioside
Definition: A diterpene glycoside that is rubusoside in which the hydroxy group at position 2 of the allylic beta-D-glucoside has been converted to the corresponding beta-D-glucoside. It is a natural herbal sweetener that is 250-300 times sweeter than sucrose (though with a bitter aftertaste), extracted from the Stevia rebaudiana plant native to South America.
Chemical ID: MESH:C012043
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pf4increases expressionISOPF4 (Homo sapiens)6480464CTDstevioside results in increased expression of PF4 mRNAPMID:31655124
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