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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3242
Species: Rattus norvegicus
RGD Object: Gene
Symbol: P2ry1
Name: purinergic receptor P2Y1
Acc ID: CHEBI:15422
Term: ATP
Definition: An adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways.
Chemical ID: MESH:D000255
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
P2ry1multiple interactionsEXP 6480464CTD[N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate binds to and results in decreased activity of P2RY1 protein] inhibits the reaction [Adenosine Triphosphate results in increased uptake of Calcium]PMID:16973929
P2ry1affects activityISOP2ry1 (Mus musculus)6480464CTDAdenosine Triphosphate affects the activity of P2RY1 proteinPMID:15243297
P2ry1multiple interactionsISOP2RY1 (Homo sapiens)6480464CTD[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium; Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [P2RY1 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide]]; P2RY1 protein promotes the reaction [Adenosine Triphosphate results in decreased susceptibility to Hydrogen Peroxide]; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium]PMID:12694404 PMID:22129738
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