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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3197
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Npy
Name: neuropeptide Y
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Npydecreases expressionEXP 6480464CTDGlucose results in decreased expression of NPY mRNA; Glucose results in decreased expression of NPY proteinPMID:16210367 PMID:18627777
Npyincreases expressionEXP 6480464CTDGlucose deficiency results in increased expression of NPY mRNA; Glucose results in increased expression of NPY proteinPMID:11177238 PMID:31778773
Npymultiple interactionsEXP 6480464CTD17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Dexamethasone inhibits the reaction [Glucose results in increased expression of NPY protein]]; Dexamethasone inhibits the reaction [Glucose results in increased expression of NPY protein]PMID:31778773
Npymultiple interactionsISONpy (Mus musculus)6480464CTD[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of NPY mRNAPMID:37567420
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