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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3171
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfkbia
Name: NFKB inhibitor alpha
Acc ID: CHEBI:167830
Term: isorhapontigenin
Definition: A stilbenol that is trans-stilbene in which one of the phenyl groups is substituted by hydroxy groups at positions 3 and 5, while the other phenyl group is substituted by a methoxy group at position 3 and a hydroxy group at position 4. It natural product isolated from the seeds of Aiphanes aculeata and has antioxidant, anti-tumour, and anti-inflammatory effects.
Chemical ID: MESH:C432307
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkbiamultiple interactionsEXP 6480464CTDisorhapontigenin affects the degradation of and affects the phosphorylation of NFKBIA proteinPMID:15607907
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