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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3112
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc1
Name: ATP binding cassette subfamily C member 1
Acc ID: CHEBI:34477
Term: 6beta-hydroxytestosterone
Definition: A 17beta-hydroxy steroid that is testosterone bearing an additional hydroxy substituent at the 6beta-position.
Chemical ID: MESH:C025591
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc1multiple interactionsISOAbcc1 (Mus musculus)6480464CTD[[ABCC1 gene mutant form results in increased susceptibility to Testosterone deficiency] which results in decreased hydroxylation of Testosterone] which results in decreased chemical synthesis of 6 beta-hydroxytestosteronePMID:22522787
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