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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2943
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Jun
Name: Jun proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:15738
Term: staurosporine
Definition: An indolocarbazole alkaloid that has formula C28H26N4O3.
Chemical ID: MESH:D019311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Junincreases phosphorylationEXP 6480464CTDStaurosporine results in increased phosphorylation of JUN proteinPMID:9751194
Junmultiple interactionsEXP 6480464CTDStaurosporine inhibits the reaction [Acetaldehyde results in increased expression of JUN mRNA]PMID:7945571
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