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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2901
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il6
Name: interleukin 6
Acc ID: CHEBI:27375
Term: vincaleukoblastine
Definition: A vinca alkaloid that has formula C46H58N4O9.
Chemical ID: MESH:D014747
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il6decreases chemical synthesisISOIL6 (Homo sapiens)6480464CTDVinblastine results in decreased chemical synthesis of IL6 proteinPMID:16499908
Il6increases stabilityISOIL6 (Homo sapiens)6480464CTDVinblastine results in increased stability of IL6 mRNAPMID:16499908
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