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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2826
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hprt1
Name: hypoxanthine phosphoribosyltransferase 1
Acc ID: CHEBI:27878
Term: 2-naphthylamine
Definition: A naphthylamine carrying the amino group at position 2.
Chemical ID: MESH:D015081
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hprt1multiple interactionsISOHPRT1 (Homo sapiens)6480464CTDNAT2 polymorphism affects the reaction [2-Naphthylamine results in increased mutagenesis of HPRT1 gene]PMID:36040704
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