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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2737
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Grin2a
Name: glutamate ionotropic receptor NMDA type subunit 2A
Acc ID: CHEBI:8502
Term: 6-propyl-2-thiouracil
Definition: A pyrimidinethione consisting of uracil in which the 2-oxo group is substituted by a thio group and the hydrogen at position 6 is substituted by a propyl group.
Chemical ID: MESH:D011441
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Grin2adecreases expressionEXP 6480464CTDPropylthiouracil results in decreased expression of GRIN2A mRNAPMID:24780913
Grin2amultiple interactionsEXP 6480464CTD[Thioctic Acid co-treated with Propylthiouracil] results in increased expression of GRIN2A mRNAPMID:31068541
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