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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2734
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Grik4
Name: glutamate ionotropic receptor kainate type subunit 4
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Grik4decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of GRIK4 mRNAPMID:25181051 PMID:30816183 PMID:32528016
Grik4increases methylationEXP 6480464CTDbisphenol A results in increased methylation of GRIK4 genePMID:28505145
Grik4multiple interactionsEXP 6480464CTD[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of GRIK4 mRNAPMID:25607892
Grik4decreases methylationISOGRIK4 (Homo sapiens)6480464CTDbisphenol A results in decreased methylation of GRIK4 genePMID:31601247
Grik4multiple interactionsISOGRIK4 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] affects the methylation of GRIK4 genePMID:31601247
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