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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2628
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fosl2
Name: FOS like 2, AP-1 transcription factor subunit
Acc ID: CHEBI:3696
Term: cidofovir anhydrous
Definition: Cytosine substituted at the 1 position by a 3-hydroxy-2-(phosphonomethoxy)propyl group (S configuration). A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.
Chemical ID: MESH:C059262
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fosl2decreases expressionISOFOSL2 (Homo sapiens)6480464CTDCidofovir results in decreased expression of FOSL2 mRNAPMID:25596134
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