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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2624
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fn1
Name: fibronectin 1
Acc ID: CHEBI:8774
Term: ramipril
Definition: A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.
Chemical ID: MESH:D017257
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fn1multiple interactionsEXP 6480464CTDRamipril inhibits the reaction [Doxorubicin results in increased expression of FN1 protein]PMID:36636964
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