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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2587
Species: Rattus norvegicus
RGD Object: Gene
Symbol: F3
Name: coagulation factor III, tissue factor
Acc ID: CHEBI:6980
Term: monocrotaline
Definition: A pyrrolizidine alkaloid that has formula C16H23NO6.
Chemical ID: MESH:D016686
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F3multiple interactionsISOF3 (Mus musculus)6480464CTD[Monocrotaline co-treated with Lipopolysaccharides] results in increased expression of F3 protein; F3 protein promotes the reaction [[Monocrotaline co-treated with Lipopolysaccharides] results in increased expression of CXCL1 protein]; F3 protein results in increased susceptibility to [Monocrotaline co-treated with Lipopolysaccharides]PMID:22407844
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