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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2583
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ets1
Name: ETS proto-oncogene 1, transcription factor
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ets1decreases expressionISOEts1 (Mus musculus)6480464CTDEstradiol results in decreased expression of ETS1 mRNAPMID:25210133
Ets1decreases expressionISOETS1 (Homo sapiens)6480464CTDEstradiol results in decreased expression of ETS1 mRNAPMID:23094148
Ets1multiple interactionsISOEts1 (Mus musculus)6480464CTDESR1 protein promotes the reaction [Estradiol results in decreased expression of ETS1 mRNA]PMID:25210133
Ets1multiple interactionsISOETS1 (Homo sapiens)6480464CTD[Estradiol co-treated with TGFB1 protein] results in increased expression of ETS1 mRNAPMID:30165855
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