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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2520
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Drd2
Name: dopamine receptor D2
Acc ID: CHEBI:31767
Term: lead diacetate
Definition: A lead coordination entity in which a central lead(2+) atom is coordinated to two acetate ions.
Chemical ID: MESH:C008261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Drd2increases expressionEXP 6480464CTDlead acetate results in increased expression of DRD2 mRNA; lead acetate results in increased expression of DRD2 proteinPMID:23702354
Drd2multiple interactionsEXP 6480464CTD[lead acetate co-treated with Morphine] results in increased expression of DRD2 mRNA; [lead acetate co-treated with Morphine] results in increased expression of DRD2 proteinPMID:23702354
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