GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Dio1 | increases metabolic processing | ISO | DIO1 (Homo sapiens) | 6480464 | CTD | DIO1 protein results in increased metabolism of Triiodothyronine, Reverse | PMID:21565810 | Dio1 | multiple interactions | ISO | DIO1 (Homo sapiens) | 6480464 | CTD | [Aurothioglucose results in decreased activity of DIO1 protein] which affects the metabolism of Triiodothyronine, Reverse; [DIO1 protein results in increased metabolism of Triiodothyronine, Reverse] which results in increased abundance of 3,3'-diiodothyronine; [Genistein results in decreased activity of DIO1 protein] which affects the metabolism of Triiodothyronine, Reverse; [Propylthiouracil results in decreased activity of DIO1 protein] which affects the metabolism of Triiodothyronine, Reverse; [xanthohumol results in decreased activity of DIO1 protein] which affects the metabolism of Triiodothyronine, Reverse; Iodoacetates inhibits the reaction [[DIO1 protein results in increased metabolism of Triiodothyronine, Reverse] which results in increased abundance of 3,3'-diiodothyronine] | PMID:21565810 PMID:25962824 | | ||||||||||||||||||||||
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