GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp2e1 | decreases expression | EXP | | 6480464 | CTD | furan results in decreased expression of CYP2E1 mRNA; furan results in decreased expression of CYP2E1 protein | PMID:15120968 PMID:20124500 | Cyp2e1 | multiple interactions | EXP | | 6480464 | CTD | 1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde]; [[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde; [CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde | PMID:21842885 | Cyp2e1 | increases expression | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | furan results in increased expression of CYP2E1 protein | PMID:34450210 | Cyp2e1 | multiple interactions | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | rhodioloside inhibits the reaction [furan results in increased expression of CYP2E1 protein] | PMID:34450210 | | ||||||||||||||||||||||
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