GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp2e1 | increases activity | EXP | | 6480464 | CTD | methacrylonitrile results in increased activity of CYP2E1 protein | PMID:11939710 | Cyp2e1 | increases expression | EXP | | 6480464 | CTD | methacrylonitrile results in increased expression of CYP2E1 mRNA; methacrylonitrile results in increased expression of CYP2E1 protein | PMID:11939710 | Cyp2e1 | increases metabolic processing | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | CYP2E1 protein results in increased metabolism of methacrylonitrile | PMID:10215687 | Cyp2e1 | multiple interactions | ISO | Cyp2e1 (Mus musculus) | 6480464 | CTD | [CYP2E1 protein results in increased metabolism of methacrylonitrile] which results in increased abundance of Cyanides | PMID:15893539 | | ||||||||||||||||||||||
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