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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2471
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2d2
Name: cytochrome P450, family 2, subfamily d, polypeptide 2
Acc ID: CHEBI:35290
Term: 1,2-dichlorobenzene
Definition: A dichlorobenzene carrying chloro substituents at positions 1 and 2.
Chemical ID: MESH:C004726
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2d2multiple interactionsEXP 6480464CTD[2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2D2 protein; CAT protein inhibits the reaction [[2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2D2 protein]PMID:24713513
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