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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2460
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Acc ID: CHEBI:33080
Term: triphenylene
Definition: An ortho-fused polycyclic arene consisting of four fused benzene rings.
Chemical ID: MESH:C009590
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1b1increases expressionISOCYP1B1 (Homo sapiens)6480464CTDtriphenylene results in increased expression of CYP1B1 mRNAPMID:38673911
Cyp1b1multiple interactionsISOCYP1B1 (Homo sapiens)6480464CTD[retene co-treated with benzo(a)fluorene co-treated with benzo(b)fluorene co-treated with benzo(c)fluorene co-treated with triphenylene co-treated with benzo(e)pyrene co-treated with 1,12-benzoperylene] results in increased expression of CYP1B1 mRNAPMID:38673911
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