GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp17a1 | decreases activity | EXP | | 6480464 | CTD | prochloraz results in decreased activity of CYP17A1 protein | PMID:16375936 PMID:17234647 PMID:17369198 | Cyp17a1 | increases expression | EXP | | 6480464 | CTD | prochloraz results in increased expression of CYP17A1 mRNA; prochloraz results in increased expression of CYP17A1 protein | PMID:16375936 | Cyp17a1 | multiple interactions | EXP | | 6480464 | CTD | [prochloraz results in decreased activity of CYP17A1 protein] which results in decreased chemical synthesis of Testosterone | PMID:17234647 PMID:17369198 | Cyp17a1 | decreases activity | ISO | CYP17A1 (Homo sapiens) | 6480464 | CTD | prochloraz results in decreased activity of CYP17A1 protein | PMID:19733639 | Cyp17a1 | decreases expression | ISO | CYP17A1 (Homo sapiens) | 6480464 | CTD | prochloraz results in decreased expression of CYP17A1 mRNA | PMID:19733639 PMID:25324206 | Cyp17a1 | multiple interactions | ISO | CYP17A1 (Homo sapiens) | 6480464 | CTD | prochloraz results in decreased expression of and results in decreased activity of CYP17A1 protein | PMID:25324206 | |
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