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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2366
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc2
Name: ATP binding cassette subfamily C member 2
Acc ID: CHEBI:34674
Term: dextran sulfate
Definition: A polymer composed of repeating (1->6)-alpha-linked anhydroglucose sulfate units.
Chemical ID: MESH:D016264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc2affects response to substanceISOAbcc2 (Mus musculus)6480464CTDABCC2 protein affects the susceptibility to Dextran SulfatePMID:30701287
Abcc2decreases expressionISOAbcc2 (Mus musculus)6480464CTDDextran Sulfate results in decreased expression of ABCC2 mRNA; Dextran Sulfate results in decreased expression of ABCC2 proteinPMID:27580383
Abcc2multiple interactionsISOAbcc2 (Mus musculus)6480464CTDABCC2 protein affects the susceptibility to [Dextran Sulfate co-treated with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine]PMID:30701287
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