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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2325521
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mir381
Name: microRNA 381
Acc ID: CHEBI:4466
Term: dexmedetomidine
Definition: A medetomidine that has formula C13H16N2.
Chemical ID: MESH:D020927
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mir381multiple interactionsISOMir381 (Mus musculus)6480464CTD[Dexmedetomidine co-treated with Lipopolysaccharides] results in increased expression of MIR381 mRNA; MIR381 mRNA affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; MIR381 mRNA affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]PMID:30102002
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