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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2325364
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mir497
Name: microRNA 497
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mir497decreases expressionEXP 6480464CTDStreptozocin results in decreased expression of MIR497PMID:35478295
Mir497multiple interactionsEXP 6480464CTDMIR497 inhibits the reaction [Streptozocin results in decreased expression of MIR497 protein]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 mRNA]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 protein]PMID:35478295
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