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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2293809
Species: Homo sapiens
RGD Object: Gene
Symbol: HOTAIR
Name: HOX transcript antisense RNA
Acc ID: CHEBI:641
Term: N-methyl-4-phenylpyridinium
Definition: A pyridinium ion that is N-methylpyridinium having a phenyl substituent at the 4-position.
Chemical ID: MESH:D015655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HOTAIRincreases expressionEXP 6480464CTD1-Methyl-4-phenylpyridinium results in increased expression of HOTAIR mRNAPMID:32968928
HOTAIRmultiple interactionsEXP 6480464CTDHOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of MIR326 mRNA]; HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP1 protein]; HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CASP1 mRNA]; HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of ELAVL1 mRNA]; HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of ELAVL1 protein]; HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of IL1B mRNA]; HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of IL6 mRNA]; HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of IL6 protein]; HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 mRNA]; HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein]; HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of PYCARD mRNA]; HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of PYCARD protein]; HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased secretion of and results in increased cleavage of IL1B protein]; HOTAIR affects the reaction [MIR326 affects the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP1 protein]]; HOTAIR affects the reaction [MIR326 affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of IL1B mRNA]]; HOTAIR affects the reaction [MIR326 affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of IL6 mRNA]]; HOTAIR affects the reaction [MIR326 affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of IL6 protein]]; HOTAIR affects the reaction [MIR326 affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NLRP3 protein]]; HOTAIR affects the reaction [MIR326 affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of PYCARD protein]]; HOTAIR affects the reaction [MIR326 affects the reaction [1-Methyl-4-phenylpyridinium results in increased secretion of and results in increased cleavage of IL1B protein]]; MIR326 affects the reaction [HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of ELAVL1 mRNA]]; MIR326 affects the reaction [HOTAIR affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of ELAVL1 protein]]PMID:32968928
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