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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cat
Name: catalase
Acc ID: CHEBI:4035
Term: cyhalothrin
Definition: A carboxylic ester obtained by formal condensation between 3-(2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol.
Chemical ID: MESH:C037304
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Catdecreases activityEXP 6480464CTDcyhalothrin results in decreased activity of CAT proteinPMID:26645134 PMID:27348886 PMID:28058584
Catmultiple interactionsEXP 6480464CTD[cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the activity of CAT protein; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in increased activity of CAT protein; thymoquinone inhibits the reaction [cyhalothrin results in decreased activity of CAT protein]PMID:26645134 PMID:33396045 PMID:35678313
Catincreases activityISOCAT (Homo sapiens)6480464CTDcyhalothrin results in increased activity of CAT proteinPMID:36529352
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