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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cat
Name: catalase
Acc ID: CHEBI:18406
Term: AICA ribonucleotide
Definition: A 1-(phosphoribosyl)imidazolecarboxamide that is acadesine in which the hydroxy group at the 5' position has been converted to its monophosphate derivative.
Chemical ID: MESH:C031143
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Catincreases expressionISOCAT (Homo sapiens)6480464CTDAICA ribonucleotide results in increased expression of CAT mRNA; AICA ribonucleotide results in increased expression of CAT proteinPMID:25065674
Catmultiple interactionsISOCAT (Homo sapiens)6480464CTDAICA ribonucleotide promotes the reaction [FOXO1 protein results in increased expression of CAT mRNA]PMID:25065674
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