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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cat
Name: catalase
Acc ID: CHEBI:15551
Term: prostaglandin E2
Definition: Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins.
Chemical ID: MESH:D015232
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Catmultiple interactionsEXP 6480464CTDCAT protein promotes the reaction [IL1B protein results in increased abundance of Dinoprostone]PMID:11286988
Catdecreases abundanceISOCAT (Homo sapiens)6480464CTDCAT protein results in decreased abundance of DinoprostonePMID:10899936
Catmultiple interactionsISOCAT (Homo sapiens)6480464CTDN-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [CAT protein results in decreased abundance of Dinoprostone]PMID:10899936
Catmultiple interactionsISOCat (Mus musculus)6480464CTDDinoprostone inhibits the reaction [PTGS1 gene mutant form promotes the reaction [Carbon Tetrachloride results in decreased expression of CAT mRNA]]PMID:25432964
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